Interpreting Diagnostic Tests

Thomas G. Tape, MD

University of Nebraska Medical Center

Basic Concepts

  • Introduction
  • Definition of sensitivity, specificity, and predictive value
  • How to evaluate a 2 by 2 table
  • Practice working with 2 by 2 tables
  • Understanding and Using Likelihood Ratios

  • Introduction
  • Likelihood ratios for tests with only two possible results
  • Computing likelihood ratios from sensitivity and specificity
  • Likelihood ratios for tests with more than two possible results
  • Using likelihood ratios to analyze a series of tests
  • ROC Curves

  • Introduction to ROC Curves
  • Plotting and interpreting an ROC curve
  • The area under an ROC curve
  • Measuring the effect size of an intervention